Can the immune system be reset in transplantation and autoimmunity?

Can the immune system be reset in transplantation and autoimmunity?

A series of 4 reviews from the RTCure consortium is out and tells you all you wanted to know about curing autoimmunity but were afraid to ask...

The author accepted versions of the articles can be found here:

777537_RTCure_D6.8_Compendium on current researches for inducing clinical therapeutic tole

Download 8_COMPENDIUM ON CURRENT RESEARCHES FOR INDUCING CLINICAL THERAPEUTIC TOLE • 14.10MB

And the publications in Lancet Review Rheumatology here:

Stanway, J. A. and Isaacs, J. D. (2020). Tolerance-inducing medicines in autoimmunity: rheumatology and beyond. The Lancet Rheumatology. 2(9): e565-e575.

DOI: https://doi.org/10.1016/S2665-9913(20)30100-4

Nel, H. J., Malmström, V., Wraith, D. C. and Thomas, R. (2020). Autoantigens in rheumatoid arthritis and the potential for antigen-specific tolerising immunotherapy. The Lancet Rheumatology. 2(11): e712-e723. DOI: https://doi.org/10.1016/S2665-9913(20)30344-1

Toes, R. E. and Raza, K. (2021) The autoimmune response as a potential target for tolerance induction before the development of rheumatoid arthritis. The Lancet Rheumatology. 3.3 (2021): e214-e223.

DOI: https://doi.org/10.1016/S2665-9913(20)30445-8

Baker, K. F., Sim, J. P., and Isaacs, J. D. (2021). Biomarkers of tolerance in immune-mediated inflammatory diseases: a new era in clinical management? The Lancet Rheumatology. 3(5): e371-e382.

DOI: https://doi.org/10.1016/S2665-9913(21)00069-2